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About Us

Biomedical Informatics & Genomics Center (BIGC) is affiliated to the biomedical and Health Engineering Research Institute of Western China Science and Technology Innovation Harbour. Relying on the Key Laboratory of biomedical information engineering of Ministry of education of Xi'an Jiaotong University, BIGC is an interdisciplinary scientific research and innovation platform. It mainly uses modern molecular biology, molecular genetics, statistical genetics, bioinformatics and other multidisciplinary methods, combined with the innovation in theory and method of our laboratory, to carry out systematic genetic research on human complex diseases. It provides theoretical guidance for disease early prediction and genetic screening, and provides new targets for new drug development.

Acknowledgement

This work was supported by grants from the National Natural Science Foundation of China (32170616, 82170896, 31970569 and 82101601), Science Fund for Distinguished Young Scholars of Shaanxi Province (2021JC-02), Innovation Capability Support Program of Shaanxi Province (2022TD-44), and the Fundamental Research Funds for the Central Universities. This work was also supported by the High-Performance Computing Platform and Instrument Analysis Center of Xi’an Jiaotong University. We would like to thank the UK Biobank and Cross-Disorder Group of the Psychiatric Genomics Consortium for the GWAS summary data of IDPs and psychiatric disorders. We also thank the US Million Veteran Program and dbGaP, the GWAS summary data of PTSD we used available from dbGaP database under dbGaP accession (phs001672.v1.p1). We thank the UK Biobank Resource under the application number 46387.

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